Research Insights Episodes

Delve into discussions about recent research findings, emerging therapies, and expert insights that shape the understanding of multiple sclerosis.
457
June 1, 2026

Episode 457: From the 2026 CMSC Annual Meeting with Dr. Kathy Zackowski, Dr. Valerie Block, and Dr. Riley Bove

Last week, the Consortium of Multiple Sclerosis Centers, best known as CMSC, hosted its annual meeting in Charlotte, North Carolina, where we had a chance to talk with some of the world's top MS experts. We'll be sharing those conversations over the next few episodes of the podcast. Welcome to Part One of our coverage of CMSC 2026! In what has become an annual tradition at this conference, Dr. Kathy Zackowski, the National MS Society's Associate Vice-President of Research, joins me to share her...
Episode 457: From the 2026 CMSC Annual Meeting with Dr. Kathy Zackowski, Dr. Valerie Block, and Dr. Riley Bove
RealTalk MS
Episode 457: From the 2026 CMSC Annual Meeting with Dr. Kathy Zackowski, Dr. Valerie Block, and Dr. Riley Bove
456
May 25, 2026

Episode 456:The First 100 Days Following Your MS Diagnosis with Dr. Nancy Sicotte

May 30th is World MS Day! This year, the theme for World MS Day is "My MS Diagnosis," and I've been thinking about what happens right after that diagnosis. After an individual hears, "You have MS." This week, Dr. Nancy Sicotte joins me to discuss the things you should know, the things you should be thinking about, and the things you should be doing in the first 100 days following an MS diagnosis. Dr. Sicotte is the Chair of Neurology and Director of Multiple Sclerosis and Neuroimmunology at Ce...
Episode 456:The First 100 Days Following Your MS Diagnosis with Dr. Nancy Sicotte
RealTalk MS
Episode 456:The First 100 Days Following Your MS Diagnosis with Dr. Nancy Sicotte
455
May 18, 2026

Episode 455: MS and Your Oral Health with Dr. Ann Spolarich

When we talk about managing Multiple Sclerosis, our conversations naturally focus on things like disease-modifying therapies, mobility, MRI scans, and symptom management. But in this week's episode, we're shining a light on a critical aspect of MS wellness that doesn't get nearly enough attention: your oral health. Living with MS can introduce a whole host of unexpected challenges to maintaining a healthy mouth. And beyond preventing tooth decay and gum disease, emerging research suggests that ...
Episode 455: MS and Your Oral Health with Dr. Ann Spolarich
RealTalk MS
Episode 455: MS and Your Oral Health with Dr. Ann Spolarich
453
May 4, 2026

Episode 453: MS and Pregnancy with Dr. Riley Bove

For decades, an MS diagnosis came with outdated advice and significant uncertainty regarding starting a family. Today, the conversation has shifted from "Is it possible?" to "How do we optimize the journey?" This week, we're taking a deep dive into the essential considerations for family planning, managing MS during pregnancy, and the crucial postpartum period. We're joined by Dr. Riley Bove, an Associate Professor of Neurology at UCSF and a leading expert in hormonal influences on MS. Dr. Bove...
Episode 453: MS and Pregnancy with Dr. Riley Bove
RealTalk MS
Episode 453: MS and Pregnancy with Dr. Riley Bove
452
April 29, 2026

Episode 452: Why Natural Myelin Repair Stops Working for People with MS (And How It Could Be Re-Started!) with Dr. Larry Sherman

Myelin repair is a natural function. But, for people living with MS, that ability to repair myelin eventually stops working. New research led by my guest, Dr. Larry Sherman, may explain why that happens and point to new possibilities for future myelin repair treatments. Dr. Sherman is a professor at the Oregon National Primate Research Center at Oregon Health & Science University, and his research focuses on how the brain and spinal cord respond to injury and disease, particularly in demyelinat...
Episode 452: Why Natural Myelin Repair Stops Working for People with MS (And How It Could Be Re-Started!) with Dr. Larry Sherman
RealTalk MS
Episode 452: Why Natural Myelin Repair Stops Working for People with MS (And How It Could Be Re-Started!) with Dr. Larry Sherman
451
April 20, 2026

Episode 451: Meet the 2026 Winner of the John Dystel Prize for MS Research with Dr. Ludwig Kappos

The annual meeting of the American Academy of Neurology is underway in Chicago this week, and one of the highlights is the presentation of the John Dystel Prize for Research in Multiple Sclerosis, awarded jointly by the National MS Society and the American Academy of Neurology. This year's winner of the Dystel Prize is Dr. Ludwig Kappos, a physician-scientist at the University Hospital Basel in Basel, Switzerland, and the director of the Research Center for Clinical Neuroimmunology and Neurosci...
Episode 451: Meet the 2026 Winner of the John Dystel Prize for MS Research with Dr. Ludwig Kappos
RealTalk MS
Episode 451: Meet the 2026 Winner of the John Dystel Prize for MS Research with Dr. Ludwig Kappos
450
April 13, 2026

Episode 450: Exercise is Medicine for People with MS with Dr. Robert Motl

An exercise program can be hard to start and even more difficult to stick with. But the evidence-based benefits speak for themselves. For people living with MS, it can mean improving quality of life without having to rely on a pill, injection, or infusion. And exercise is 100% affordable! Dr. Robert Motl, the Director of the Exercise Neuroscience Research Laboratory at the College of Applied Health Sciences at the University of Illinois Chicago, joins me to discuss how exercise can improve MS-r...
Episode 450: Exercise is Medicine for People with MS with Dr. Robert Motl
RealTalk MS
Episode 450: Exercise is Medicine for People with MS with Dr. Robert Motl
449
April 6, 2026

Episode 449: Putting People Affected by MS at the Center of MS Research with Sara Loud, Stephanie Buxhoeveden, and Hollie Schmidt

When you join the iConquer MS community, you're no longer just a patient; you become a research partner. Not just a data point in someone's study. You become the person to suggest the study, to help define the study, and to participate in sharing the outcome of the study. In this week's episode, I talk with the iConquer MS leadership team about what it means to be part of this people-powered research revolution and how iConquer MS keeps people affected by MS at the center of MS research. The Na...
Episode 449: Putting People Affected by MS at the Center of MS Research with Sara Loud, Stephanie Buxhoeveden, and Hollie Schmidt
RealTalk MS
Episode 449: Putting People Affected by MS at the Center of MS Research with Sara Loud, Stephanie Buxhoeveden, and Hollie Schmidt
444
March 2, 2026

Episode 444: Treating MS with a GLP-1 with Dr. Ellen Mowry

You know them by their trade names such as Ozempic, Wegovy, Mounjaro, and Zepbound. This class of medications is known as GLP-1 receptor agonists. And while they are best known for managing diabetes and promoting weight loss, researchers are finding that these drugs are also effective in a broad range of other health conditions. So, what about MS? My guest this week is Dr. Ellen Mowry, the principal investigator of a clinical trial to determine whether a GLP-1 drug can reduce brain inflammation...
Episode 444: Treating MS with a GLP-1 with Dr. Ellen Mowry
RealTalk MS
Episode 444: Treating MS with a GLP-1 with Dr. Ellen Mowry
443
Feb. 23, 2026

Episode 443: The 2026 ACTRIMS Forum (Part 3) with Dr. Helen Tremlett, Dr. Ilana Katz Sand, and Kathy Smith

Welcome back to the third and final part of our coverage of the 2026 ACTRIMS Forum. This week's episode bridges the gap between groundbreaking clinical research and the nuanced reality of living with MS every day. First, we'll dive into the "before" and "after" of a diagnosis, starting with Dr. Helen Tremlett's insights into the MS prodrome—those subtle, early signs that appear years before typical MS symptoms. We'll also talk with Dr. Tremlett about how other health conditions can predict long...
Episode 443: The 2026 ACTRIMS Forum (Part 3) with Dr. Helen Tremlett, Dr. Ilana Katz Sand, and Kathy Smith
RealTalk MS
Episode 443: The 2026 ACTRIMS Forum (Part 3) with Dr. Helen Tremlett, Dr. Ilana Katz Sand, and Kathy Smith